Sniffles v2.3
This release includes new features for multisample calling and some restructuring of the codebase to facilitate easier development in the future.
New features:
-
Multisample calling for large input sets
Sniffles multiprocessing code has undergone a major rewrite with focus of enabling multisample calling for a large number of input files. To support this, the new optional dependency psutil can be installed along with sniffles. -
Using alignments for multisample calling
Alignments can be used to improve separation of variants in multisample calling. This uses the new optional dependency edlib and can be tweaked with the new argument--combine-pctseq
defaulting to 0.7.
Required Python version has been updated to Python 3.10.