diff --git a/src/ReverseProxy/Transforms/RequestTransformContext.cs b/src/ReverseProxy/Transforms/RequestTransformContext.cs
index 74d87f21e..52255e428 100644
--- a/src/ReverseProxy/Transforms/RequestTransformContext.cs
+++ b/src/ReverseProxy/Transforms/RequestTransformContext.cs
@@ -53,8 +53,9 @@ public QueryTransformContext Query
     /// <summary>
     /// The URI prefix for the proxy request. This includes the scheme and host and can optionally include a
     /// port and path base. The 'Path' and 'Query' properties will be appended to this after the transforms have run.
+    /// Changing this value can have side effects on load balancing and health checks.
     /// </summary>
-    public string DestinationPrefix { get; init; } = default!;
+    public string DestinationPrefix { get; set; } = default!;
 
     /// <summary>
     /// A <see cref="CancellationToken"/> indicating that the request is being aborted.
diff --git a/test/ReverseProxy.Tests/Transforms/DestinationPrefixTransformTests.cs b/test/ReverseProxy.Tests/Transforms/DestinationPrefixTransformTests.cs
new file mode 100644
index 000000000..c6b6ba8be
--- /dev/null
+++ b/test/ReverseProxy.Tests/Transforms/DestinationPrefixTransformTests.cs
@@ -0,0 +1,31 @@
+// Copyright (c) Microsoft Corporation.
+// Licensed under the MIT License.
+
+using System.Threading.Tasks;
+using Xunit;
+
+namespace Yarp.ReverseProxy.Transforms.Tests;
+
+public class DestinationPrefixTransformTests
+{
+    [Fact]
+    public async Task UpdateDestinationPrefix()
+    {
+        const string newDestinationPrefix = "http://localhost:8080";
+        var context = new RequestTransformContext()
+        {
+            DestinationPrefix = "http://contoso.com:5000"
+        };
+        var transform = new DestinationPrefixTransform(newDestinationPrefix);
+        await transform.ApplyAsync(context);
+    }
+
+    private class DestinationPrefixTransform(string newDestinationPrefix) : RequestTransform
+    {
+        public override ValueTask ApplyAsync(RequestTransformContext context)
+        {
+            context.DestinationPrefix = newDestinationPrefix;
+            return ValueTask.CompletedTask;
+        }
+    }
+}