diff --git a/packages/interface/CHANGELOG.md b/packages/interface/CHANGELOG.md
index 64f8c370bb6ece..27542772506d44 100644
--- a/packages/interface/CHANGELOG.md
+++ b/packages/interface/CHANGELOG.md
@@ -2,6 +2,10 @@
 
 ## Unreleased
 
+### Breaking Changes
+
+-   `InterfaceSkeleton` no longer supports region navigation and its props `enableRegionNavigation` and `shortcuts` are removed. ([#63611](https://github.com/WordPress/gutenberg/pull/63611)). It’s recommended to add region navigation with the higher-order component `navigateRegions` or the hook `__unstableUseNavigateRegions` from `@wordpress/components`.
+
 ## 6.7.0 (2024-09-05)
 
 ## 6.6.0 (2024-08-21)